If you have diabetes, then I am sure that you have had – or are about to have – a battery of blood tests. One of those tests is the A1C test that every diabetic is required to have. So what is it?
The A1C test measures the percent of glucose-containing red blood cell molecules in the bloodstream. Now, I realize that none of that makes sense until you understand what all of these words mean.
Hemoglobin A is a protein in red blood cells that is used to transport oxygen from the lungs to the rest of the body. When glucose molecules combine with hemoglobin A in the bloodstream, the hemoglobin A1C molecule is created. Following me? Good. Now here is the kicker: the more glucose in the bloodstream, the more hemoglobin A1C molecules are created. Right? Right. Now that we understand that part, we can go on to what the A1C test measures.
The A1C test measures the percentage of hemoglobin A1C molecules that have formed in the bloodstream. If you have your A1C tested and the result is say, 5, then 5% of the hemoglobin A in the bloodstream has glucose stuck to it and has become hemoglobin A1C. Make sense? In other words, if your A1C is 5, then 5% of the hemoglobin in the bloodstream is hemoglobin A1C. For those of us with diabetes, it is suggested that we try and keep the A1C at or below 7 percent. It is also suggested by the American Diabetes Association that the A1C test be repeated every three months to check for consistency.
Understanding diabetes is tough. Hopefully, understanding the A1C is not.
Posts Tagged ‘Red Blood Cell’
A large percentage of chronic kidney failure patients suffer from anemia, but what makes them so susceptible to this problem?
Most people think their kidneys do only one thing – purify the blood. But among other things, the kidneys secrete the important hormone erythropoietin (also known as EPO), which controls red blood cell production (the amount of iron in your diet is also important). The EPO tells your bone marrow to make more red blood cells. As kidney failure progresses (indeed even before you know you are suffering from kidney failure), your kidneys ability to produce erythropoietin is reduced, so your bone marrow receives less signals to spring into action and so less red blood cells are produced. This is anemia.
As the concentration of red blood cells reduces, your blood carries less and less oxygen, and symptoms of anemia start to be obvious when your kidneys have dropped to around 45% of their usual ability. As kidney failure increases, you become more anemic. Telltale signs of anemia are fatigue, shortness of breath, feeling cold all the time, looking pale, problems concentrating, headaches, and sometimes chest pains. Women also have changes in their period, while men may have trouble with erections.
Your heart now has to work harder than normal, because with less red blood cells and thus less oxygen being carried by your blood, you need more blood pumping around to give you a chance of extracting enough oxygen as you go about your daily life. This in turn can lead to heart problems (and a surprisingly large percentage of chronic kidney failure patients have heart problems). One of the four heart chambers enlarges and chronic kidney failure patients suffer often suffer from left ventricular hypertrophy, also known as LVH.
So if you have several of the symptoms of anemia listed above, it is important to see your doctor and have anemia blood tests carried out. Your doctor will probably also recommend that you have some tests for kidney failure carried out as well, just to be on the safe side.
Fortunately anemia can be treated. This usually involves for kidney failure patients injections of EPO and iron supplements. (Iron supplements, because if the iron content of your body is too low, EPO can’t do its job properly – red blood cells have iron as an important constituent, present in haemoglobin as the part of the molecule that carries the oxygen around.)
As your diet can affect the amount of iron in your body, and hence your ability to produce red blood cells, you may also wish to consult your renal dietary consultant – it isn’t simply a case of eating any food that contains iron. Some foods increase your ability to excrete iron, and some combinations of foods are not suitable for kidney dialysis patients.
As kidney failure patients have a hard enough time as it is, reducing problems due to anemia makes life a little bit more bearable for them. One last word – if you see a charity or hospital asking for help to buy dialysis machines – give generously.
Endometriosis which grow somewhere else other than the endometrium also reacts to hormonal signals of the monthly menstrual cycle by building up tissue, breaking it, and eliminating it through the menstrual period. As we know, nutritional supplements play a very important role in treating endometriosis. In this article, we will discuss how vitamins help to treat endometriosis.
A. Vitamin A
I. Definition
Vitamin A is a bi-polar molecule formed by bonds between carbon and hydrogen. It is a fat soluble vitamin. This means it can not be stored in the liver but it can be converted from beta-carotene, a powerful antioxidant. Besides helping in treating endometriosis, it is also known to have strong effects in improving vision and enhancing bone growth.
II. Vitamin A and endometriosis
a) Vitamin A is a very powerful antioxidant that not only helps to strengthen the immune system, but also protects against the growth of endometriosis.
b) Vitamin A helps in regulating the gene expression by fighting against the forming of free radicals and protecting the body organs from abnormal growth of endometrial implants and adhesion.
c) Red blood cell production
Vitamin A working together with iron helps to aid the production of red blood cells and improve the oxygen level in the circulation of blood which is necessary for the body’s cells. This results in a stronger immune system as well as protecting the forming of abnormal cells.
d) Working together with Zinc
Zinc deficiency interferes with
a) Vitamin A function of protein synthesis and fatty acid metabolism.
b) Reducing the activity of enzyme that release vitamin A palmitate from the liver causing a weakened immune system fighting against the forming of free radicals, and endometrial implants, and adhesion.
e) Work together with iron
Iron is necessary for production of red blood cells that carry oxygen in the blood stream for the body’s cells. Women who have endometriosis with heavy blood loss during menstruation normally have iron deficiency because of loss of iron which is far greater than what the body can produce leading to anemia. Intake of vitamin A and iron will increase the production of red blood cells far better than taking iron supplements alone.
Remember, overloading on zinc or iron is toxic to our body. Please make sure to talk to your doctor for the correct amount.
B. Vitamin B1
I. Definition
Vitamin B1 is one of the members of the vitamin B complex, it is also known as thiamin or thiamine. It’s most common form is a colorless chemical compound with the formula C12H17N4OS. It was discovered in 1910 by Umetaro Suzuki in Japan. It is a water soluble vitamin, therefore it can be stored in the body and is required to be taken regularly.
II. How Vitamin B1 benefits women with endometriosis
Women with endometriosis are found to have vitamin B complex deficiency during the menstrual cycle. It is not known if it is caused by unhealthy diet or the inability of digestive absorption.
a) Level of estrogen
Vitamin B1 helps to detoxify the liver which may be caused by intake of of alcohol, smoking and heavy metals. A strong liver is particularly important for secretion of cholesterol in breaking down estrogen that causes menstrual cramps as well as hormone balancing in the body.
b) Immune system
Vitamin B1 is an antioxidant that helps to strengthen the immune system against the forming of free radicals, endometrial implants, and adhesion somewhere else in the body except the endometrium.
c) Red blood cells
Study shows that vitamin B1 helps to normalize the activity of an enzyme called transketolase in red blood cells resulting in increased amounts of the two proteins THTR-1 and RFC-1 which helps to transport thiamine into red blood cells. This increases the production of red blood cells in the bloodstream.
d) Nervous system
It helps to reduce tension of the nervous system as a resulting of converting carbohydrates to energy which is necessary for the proper functions of the nervous system. Thereby it reduces symptoms of endometriosis in some women such as anxiety, depression, and mood swings.
e) Intestine muscle tone
Vitamin B1 helps to secrete hydrochloric acid in the stomach which is essential for the complete digestion of food particles and decreases the risk of nutrient deficiency causing hormone imbalance in the menstrual cycle.
C. Vitamin B2
I. Definition
Vitamin B2 is water soluble, also known as riboflavin. It has a chemical compound formula of C17H20N4O6. Like many other vitamin B complexes, it plays an important role in providing energy to our body by the metabolism of fat, carbohydrates and protein.
II. How vitamin B2 helps to treat endometriosis
1. Red blood cell formation
Vitamin B2 includes the active co-enzyme forms of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) that helps to transport vitamin b2 into the red blood cell as well as maintaining the red blood cell formation.
2. Strengthens the immune system
Vitamin B2 is an antioxidant that helps to rejuvenate the immune system caused by toxins accumulated in the liver that helps to maintain our body’s function fighting against any abnormality of cell growth including abnormal endometrial cells.
3. Cell growth
Since vitamin B2 helps in protein metabolism, it helps to maintain normal cell division or cell growth which decreases the risk of cell abnormality and prevent endometrial cells to grow somewhere else in the body excluding the endometrium.
4. Iron and vitamin B6
Vitamin B2 is needed for a healthy mucus membrane in the digestive system. It enhances the absorption of iron and vitamin B6 which is essential for women with endometriosis and heavy flow during menstruation.
5. Migraine
The Riboflavin that is found in Vitamin B2 has shown beneficial results by assisting in decreasing the time as well as the frequency in which one gets a migraine headache due to symptoms of endometriosis during menstruation.
6. Nervous system
Vitamin B2 can assist with alleviating stress as well as reducing symptoms of depression that are brought on by digestive disorders that generally affects women with endometriosis during the menstrual cycle.
D. Vitamin B3
I. Definition
Vitamin B3 , also known as niacin, is a water-soluble vitamin. Besides being usedto treat pellagra caused by dietary lack of vitamin B3 and protein, it also has been known to be effective in treating endometriosis because women with endometriosis are found to have vitamin B3 deficiency. It has a chemical compound formula of C6H5NO2.
II. How vitamin B3 helps in treating endometriosis
1. Hormone synthesis
Vitamin B3 is found to help the manufacturing of hormones such as cortisone and the sex hormone estrogen in a woman’s body. Besides helping to inhibit levels of bad estrogen that causes menstrual cramps during menstrual cycle, it also helps to balance the prostaglandin hormone which causes over-active uterine muscles.
2. Digestive system
Deficiency of vitamin B3 is generally found in women with endometriosis during menstruation. It may be caused by the inability of the digestive system in breaking down food particles. Intake of vitamin B3 helps to re-balance the hormones that cause menstrual cramps.
3. Metabolism of carbohydrates, proteins and fats
Besides helping to provide energy for our body in metabolism of carbohydrate through bile secretion, vitamin B3 also helps in the metabolism of protein and fat which are important for our body’s function.
4. Circulatory stimulation
Vitamin B3 also helps in stimulation of the circulatory system by reducing the level of bad cholesterol (LDL) from the arteries in some people.
5. Nervous system
Vitamin B3 is important for the healthy activity of the nervous system by providing the metabolism of protein and fat which are nutrients necessary for brain cells resulting in reduced symptoms of endometriosis such as depression, anxiety, and irritation.
6. Inflammation
Vitamin B3 increases the level of prostaglandins hormones which control the physiologic processes of blood clotting and inflammation.
E. Vitamin B5
I. Definition
Vitamin B5 is also known as pantothenic acid. It plays an important role in the forming of co-enzyme A and is critical in the metabolism and synthesis of carbohydrates, proteins and fat. Vitamin B5 has a chemical structure formula of C9H17NO5.
II. How vitamin B5 helps in treating endometriosis
Most women with endometriosis were found to have low levels of vitamin B5 during the menstrual cycle for what ever reason. Without enough vitamin B5 in a woman’s body, it causes:
1. A weakened immune system
Since vitamin B5 is necessary in the metabolism of carbohydrates, it helps to generate energy for our body’s cells. Without enough levels of vitamin B5, our body’s immune system is weakened and is dangerous for the forming of free radicals and cell abnormalities.
2. Poor circulation
Our liver is the first line of defense by secreting bile into the digestive system to produce good cholesterol, which helps to inhibit the bad cholesterol in the arteries. Without enough vitamin B5, bad cholesterol is left unchecked causing difficulty for blood circulation.
3. Increased risk of over-active uterine muscles
Liver helps in metabolism of fat. Without enough vitamin B5, it causes hormone imbalance in the prostaglandins family leading to over-reaction of uterine muscles which in turn causes abdominal pain.
4. Increased tension of nervous system
Fat and protein are important for nourishing the cells in the nervous system. Low levels of vitamin B5 weakens the brain cell’s function. This leads to symptoms of endometriosis such as anxiety, mood swings, and depression.
5. Increased risk of allergic reaction
Insufficient vitamin B5 in our body causes deficiency in co-enzyme A which is necessary for our body to react to sudden substances that enter our body, causing violently allergic reactions.
6. Acne
Fatty acid metabolism becomes less efficient and the individual is more prone to have acne.
7. Hormonal imbalance
Besides helping to reduce acne, vitamin B5 also interacts with other members of the vitamin B complex by increasing the function of the adrenal glands which is necessary to balance hormones and promote normal growth of the body.
F. Vitamin B6
I.Definition
Vitamin B6 is water soluble and a member of vitamin B complex. It plays an important role in amino acids metabolism that helps to maintain the proper function in our body.
II. Endometriosis and Vitamin B6
1. Hormone balancing
Vitamin B6 is essential for the production of the right levels of prostaglandins hormones in the prostaglandins family. Deficiency of vitamin B6 causes over active uterine muscles resulting in endometrial cramps.
2. Estrogen inhibitor
Vitamin B6 helps the live in protein and fat metabolism, thereby increasing the production of good estrogen that inhibits the bad estrogen produced by the body resulting in hormone re balancing and decrease the risk of cell abnormality and cancer.
3. Anemia
Vitamin B6 increases the production of red blood cells that usually are depleted for the women with the heavy menstrual flow during menstruation.
4. Nervous system
Our nervous system requires variety of nutrients to function daily, vitamin B6 helps not only maintain a right levels of cholesterol but also increase the circulation of nutrients to our nervous system needed resulting in decreasing the symptoms of endometriosis, such as memory loss, confusion and anxiety.
5. Cell Growth
Vitamin B6 aids in the synthesis of DNA and RNA by maintaining the proper cell division and preventing cell abnormal growth such as peritoneal cells developing into endometrial cells.
G. Vitamin B12
I. Definition
Vitamin B12 is a water soluble vitamin and a member of vitamin B complex. It plays an important role in treating women with endometriosis, such as reducing symptoms of endometriosis during menstrual cycle, maintaining protein and fat metabolism, avoiding iron deficiency, etc.
II. Endometriosis and vitamin B12
1. Anemia
Women with endometriosis are found to have low levels of vitamin B12 during menstrual cycle for what ever reason. Deficiency of Vitamin B12 deceases the production of red blood cell in the blood stream causing depletion of levels of iron in the blood leading to anemia.
2. Nervous system
Vitamin B12 is vital for protein and fat synthesis that helps to strengthen the function of nervous system resulting in lessening the nervous tension such as irritation, loss of memory, depression and mood swing.
3. Insomnia and fatigue
Besides helping in protein and fat synthesis, vitamin B12 also play an important role in carbohydrate metabolism that helps to provide energy for our body function and aids in insomnia and fatigue.
4. Immune system
Liver required vitamin B12 to function properly, deficiency of vitamin B12 causes enlarged liver resulting in decreasing the function of liver in fighting against environment toxins leading to high levels of bad estrogen in the body resulting in menstrual cramps for women with endometriosis.
5. Cell abnormality
Vitamin B12 is vital for the synthesis of DNA. Deficiency of vitamin B12 increases the risk of abnormal cell growth in the body such as endometrial cells growing somewhere else in the abdomen.
H. Biotin
I. Definition
Biotin is one of the members of the vitamin B complex. It is also known as vitamin H or B7. Vitamin B7 is a co-factor in the metabolism of fatty acids, leucine, and in gluconeogenesis. It has a chemical structure formula of C10H16N2O3S. Deficiency is extremely rare, as intestinal bacteria generally produce an excess of the body’s daily requirement but for what ever reason, women with endometriosis are found to have low levels of biotin.
II. How biotin helps in treating endometriosis
1. Cell abnormality
Biotin acts as a co-factor with the other members in the vitamin B complex. It plays an important role in managing the body’s cell growth. Without enough biotin, it causes cell growth abnormality such as the forming of perinatal cells into endometrial cell in the abdominal regions.
2. Poor blood circulation
Since biotin helps in gluconeogenesis, it regulates the sugar levels in the blood stream. Without enough levels of biotin, the level of blood sugar rises causing the thickening of blood which reduces the circulatory function and blocks the transportation of nutrients and oxygen to our body’s cells. This results in an increased risk of symptoms of endometriosis.
3. Endometrial cramps
Since biotin is necessary in the metabolism of fatty acids, it helps to maintain levels of prostaglandins. Deficiency of biotin causes some members in the prostaglandins family to be over-produced during the menstrual cycle leading to menstrual and endometrial cramps.
4. Respiratory problem
Since biotin helps to synthesize carbon dioxide, without enough biotin it causes shortness of breath in women with endometriosis.
5. Risk of heart disease and stroke
If the liver cannot produce enough bile to generate good cholesterol because of not enough amounts of biotin in the body, it leads to cholesterol building up in the arteries causing the thickening of the arterial wall and the blockage o circulation of blood resulting in an increased risk of heart disease and stroke.
6. Weaken function of nervous system
Since biotin acts as a co-factor with other vitamin B complexes in the metabolism of protein, deficiency of biotin interferes with that process. It weakens the normal functions of cells in the nervous system leading to tension of the nervous system such as anxiety, dizziness, loss of memory, and depression.
I. Folic Acids
I. Definition
Folic acid is one of the members of the vitamin B complex family and is a water soluble vitamin. It also known as vitamin M or folacin. It’s major function is to maintain normal growth and DNA of our body’s cells. It has a chemical structure formula of C19H19N7O6.
II. How folic acids helps in treating endometriosis
1. Anemia
Since folic acid deficiency limits cell division, women with endometriosis with heavy blood flow during menstruation are required to take enough folic acid to help in production of red blood cell. If not, it will lead to megaloblastic anemia.
2. Cell abnormality
Since folic acid is necessary for cell division, deficiency of it will lead to abnormality of some cells in the body. Some endometrial cells may become cancerous or grow into endometrial cells in the abdomen.
3. Protein synthesis
Folic acids interact with other members of the vitamin B complex family in the metabolism of protein. This helps to provide nutrients to the cells in the nervous system. Deficiency of folic acids cause the weakening of the nervous system leading to symptoms of endometriosis.
4. Abnormal cell growth
Folic acid is essential to normal DNA replication, DNA repair, and cell division. Deficiency of folic acid interferes with cell production and cannot repair the damage of cell caused by toxin accumulated in the body leading to abnormal cell growth.
5. Heart disease and stroke
Deficiency of folic acid may help to decrease the circulating level of homocytesteine in the blood. Study shows that high levels of homocysteine in the bloodstream damages coronary arteries or makes it easier for blood clotting, resulting in an increased risk of heart disease and stroke.
6. Endometrial cancer
Since we already know that adequate levels of folic acid helps in the synthesis, repair, and functioning of DNA. Deficiency of folic acid may result in damage to DNA that may lead to cancer.
J. Choline
I. Definition
Choline is a water soluble vitamin and belongs to the group of vitamin B complexes. It was discovered by Andreas Strecker in 1864. It is used in traditional medicine in treating heart and liver disease caused by choline deficiency.
II. How choline helps in treating endometriosis
1. Strengthens the immune system
Deficiency of choline causes fat to be deposited into the liver and reduce the function of liver to fight against the abnormal forming of endometrial implants and adhesion in other parts of the body causing inflammation.
2. Reduce risk of heart diseases
Women with endometriosis are found to have low levels of choline during their menstrual cycle. The causes of deficiency are still unknown. Choline interacts with other members in the vitamin B complex family to help in carbohydrate, protein and fat metabolism which are necessary to provide energy and nutrients for our body. It also helps help to strengthen the liver in bile production, which helps to reduce the level of bad cholesterol resulting in decreasing the risk of heart diseases.
3. Increase function of nervous system
Since choline is a chemical precursor needed to produce the neurotransmitter acetylcholine, it helps to enhance the various congestion systems within the brain resulting in an improved function of the nervous system leading to reduced symptoms of endometriosis such as memory loss, poor concentration, anxiety, and mood swings.
4. Balancing hormone
Deficiency of choline causes abnormal functions of the liver. Since the liver plays an important role in fatty acid metabolism, deficiency of choline weakens the liver function resulting in excessive estrogen produced during menstrual cycle leading to hormone imbalance and endometrial cramps.
K. Vitamin C
I. Definition
Vitamin C is also known as L-ascorbate. It is a water soluble vitamin with a chemical structure formula of C6H6O6. It cannot be stored in the body for more than 24 hours and we are required to take it regularly. It is also best known for it’s antioxidant property in strengthening the immune system.
II. Vitamin C and endometriosis
1. Immune system
Vitamin C plays an important role in strengthening the immune system because of it’s powerful antioxidant property. It helps to guard our body against the forming of free radicals and abnormal growth of endometrial cells in other parts of the body.
2. Increase absorption of digestive system
Most women with endometriosis are found to have deficiency of some kinds of vitamins and minerals such as vitamin B complex, folic acid, zinc, and magnesium. Increasing intake of vitamin C not only helps to improve digestive absorption, but also increases the body’s function in fighting against all kinds of diseases including endometriosis.
3. Hormone balancing
Besides helping strengthen the liver function to balance the estrogen level during menstrual cycle, vitamin C also balances the level of prostaglandins hormones in the prostaglandins family resulting in the calming of over-active uterine muscles.
4. Reduce heavy blood flow and blood clotting
Vitamin C not only helps to protect the breaking off of the capillaries that cause heavy blood flow for women with endometriosis during menstruation but also prevents blood clotting caused by reduction of prothrombin, thrombin, and thrombokinase concentrations in the body.
5. Decrease infection and inflammation
Vitamin C helps in protein metabolism. It not only provides our body with certain necessary proteins but also blocks the synthesis of vital proteins that cause infection and inflammation.
L. Vitamin E
I. Definition
Since vitamin E is a fat soluble vitamin, it can be stored in our body and we don’t require to take it regularly. It is best known for its powerful antioxidant property.
II. The effects of Vitamin E in women with Endometriosis
a) Immune system
Since vitamin E is an antioxidant, it helps to increase liver function in fighting the forming of free radicals, abnormal cells and cancers. In endometriosis, it prevents the growth of abnormal endometrial to form implants and adhesion in other parts of the body excluding the endometrium.
b) Cell protection
Since vitamin E protects the fatty acid against degradation in the human body, it helps to prevent against the oxidation in cell membranes and cellular regions resulting in protecting against the breaking off of the capillary wall causing heavy blood flow during menstruation.
c) Red blood cells
Deficiency of vitamin E in women with endometriosis were also found to have anemia. It is caused by the faster than normal aging of red blood cells because of oxidative destruction of red blood cells.
d) Nervous system
Since we already known that vitamin E is essential for increasing the ability of red blood cells to carry oxygen in the circulation system, it helps to nourish the brain cells fighting against symptoms of endometriosis such as mood swings, anxiety, and depression.
e) Hormone imbalance
Deficiency of vitamin E also interferes with normal functions of thyroid and pituitary glands causing the increase of levels of fatty acids resulting in endometrial menstrual cramps which in turn result in the over-production of certain prostaglandins hormones.
M. Vitamin K
I. Definition
Vitamin K was first discovered by Danish scientist Herrik Dam in 1929. It is a fat-soluble vitamin. It is best known for its ability of protein synthesis and blood coagulation. Dietary deficiency is extremely rare because it is produced by bacteria in the digestive system. Since it is fat soluble, it can be stored in our body and we do no need to take them regularly.
II. How vitamin K effects women with endometriosis
1. Nervous and circulation systems
Vitamin K helps to convert glucose into glycogen which is essential for improving the liver function in fighting against the forming of bad cholesterol accumulated in the blood stream causing high blood pressure, making transportation of oxygen more difficult to the body’s cell, increasing the risk of heart disease and elevating tensions of nervous system. Glycogen can be stored in the liver, muscles, and can be used in case of deficiency.
2. Abnormal bleeding
Vitamin K also helps in production of prothrombin which is an important substance for blood clotting. Women with endometriosis were found to have vitamin K deficiency leading to heavier than normal bleeding during menstruation.
3. Immune system
Since vitamin K helps to strengthen the liver’s function, indirectly it protects our body from environmental toxins that cause abnormal endometrial implants and adhesion growing somewhere else other than the endometrium as we mentioned in the other articles.
4. Cell Growth
Vitamin K is also said to be an important vitamin that helps to regulate the cellular functions including cell adhesion, cell proliferation, and protection against the cell’s cytoskeleton to break up the membrane and bulge outward causing the loss of membrane asymmetry and attachment. Deficiency of vitamin K may cause an increase in the risk of irregularity cellular growth, such as endometriosis.
5. Anemia
Since vitamin K deficiency causes heavy bleeding for women with endometriosis adhered to the abdominal region leading to anemia as a result of depletion of red blood cells in the body or inability of the body to produce more red blood cell to cover the loss during menstruation
Since endometriosis is treatable and manageable by natural remedies and a self help course, if you have endometroisis, please look on the bright side.
Pernicious anemia is a condition that results when the body cannot absorb enough vitamin B12. In this particular condition, cells that line the stomach have lost the ability to produce enough of a substance called Intrinsic Factor. Why is this important? Because Intrinsic Factor must first combine with B12 to form a B12-Intrinsic Factor complex so that the digestive system can absorb it.
We know that vitamin B12, also known as cobalamin, plays an important role in several processes: it helps make red blood cells, supports nerve cell function, and even helps build DNA. When the body’s immune system malfunctions and begins attacking the cells in the stomach that make intrinsic factor, the decrease in intrinsic factor production greatly affects B12 absorption, for the worse.
Pernicious anemia is also known in medical circles as megaloblastic anemia. The term megaloblastic describes the large, immature red blood cells that are seen in people with this condition, which is more common in persons of northern European descent. Often the terms pernicious anemia and B12 deficiency are used interchangeably, but it is important to note that pernicious anemia refers only to the B12 deficiency that happens when there is an absence of intrinsic factor.
What are the symptoms of pernicious anemia?
Weakness Fatigue Numbness tingling of hands and feet Difficulty walking Decreased appetite Weight loss Nausea Tender, smooth tongue Diarrhea Irritability Increased heart rate
Why is it important to supplement B12?
Even though the red blood cell abnormalities can be improved to normal by supplementing vitamin B12, if too much time passes before the pernicious anemia is detected, the neuropathy (nerve damage) that causes numbness and tingling can become permanent. Usually pernicious anemia is found through a routine check up and a blood test (CBC, or cell blood count) at the doctor’s office. Persons most at risk of developing it are the elderly; strict vegetarians who don’t supplement B12; and pregnant women.
An important note is that breastfed babies of vegetarian moms can easily develop vitamin B12 deficiency by age 4 to 6 months because their liver reserves–which are normally plentiful–are limited and can be depleted quickly due to their rapid growth rate, (which results in a high demand for B12). One last thing to remember is that folate supplementation should not be taken alone instead of vitamin B12 because folate may indeed alleviate the anemia but allow the neurologic (nerve) deficits to progress or even accelerate. For this reason, both B12 and folate should be supplemented together.
A condition in which there are either too few red blood cells, too little hemoglobin in each red blood cell, or both. Your child will seem quite well if he is only mildly anemic. If the anemia develops slowly, the body adapts to the smaller amount of hemoglobin. This means that even severe anemia – if it is of gradual onset may cause no symptoms. What you’ll probably notice first is that the child is abnormally tired. He may be pale- the color of his lips, fingertips and insides of the eyelids are a better guide than the cheeks. He may also have a poor appetite or be irritable.
The anemia is caused by a sudden loss of blood, as in an accident or in certain blood disorders, then there may be some breathlessness, a fast pulse and even heart failure if treatment isn’t begun.
The many possible causes fall into three main groups. Lowered red blood cells count in the body; excessive breakdown of red blood cells by the body; and blood loss.
Iron deficiency anemia is the commonest blood disorder in children. Because breast milk usually contains plenty of easily-absorbed iron, young breast-fed babies don’t often suffer from it. Some premature babies are born with low body stores of iron and so have blood tests to check for anemia from time to time. The young child who doesn’t eat a varied diet containing iron-rich foods may become anemic. The main sources of iron in our diet are meat, bread (especially wholemeal), flour, cereals, potatoes and vegetables.
About one child in three with iron deficiency anemia has slight, continual bleeding from the gut after drinking cow’s milk. This can be prevented by heating cow’s milk before it is drunk or by reducing the amount of cow’s milk drunk by the child. Large amounts of cow’s milk may also reduce the amount of iron absorbed by the body and reduce the child’s appetite for other foods.
anemia can be caused by blood loss (a severe nose bleed, an accident or an operation) certain drugs which damage bone marrow or red blood cells: abnormalities in the red cells themselves or by leukemia. Rhesus babies usually suffer from anemia due to red cell abnormalities.
The vast majority of children whose cheeks look pale aren’t anemic at all. In those that are, iron deficiency anemia is the commonest condition by far.
Nutritional iron supplements are primarily used by those with iron-deficiency anemia or conditions that lead to it, such as low hemoglobin or red blood cell count. Although iron is normally obtained from food, certain conditions increase the body’s need for iron. These include pregnancy, bleeding problems, hemodialysis, and intestinal problems. Breastfed infants and children undergoing growth spurts may also need supplemental iron.
There are different types of nutritional iron supplements, but each one serves a different purpose. It is important to choose the right iron supplement to best serve your nutritional needs. Here are some buying tips and advice on using nutritional iron supplements.
1. Read the generic names.
Nutritional iron supplements are either ferric or ferrous. Ferrous supplements are better absorbed by the body, but one should also know the amount of elemental iron in each type. Elemental iron is simply the amount of iron in the pill available for absorption. Ferrous fumarate contains 33% elemental iron, while ferrous sulfate and ferrous gluconate contain only 20% and 12% respectively.
2. Know the side effects.
The most common side effect or iron supplements is black stool, which is fairly harmless. Liquid supplements may also cause yellowing of the teeth, but the effect is reversible and can be avoided by administering through a straw. Intramuscular injections can cause considerable pain and brown discoloration of the injected area. Other common side effects are diarrhea, obstipation (severe constipation), and epigastric abdominal discomfort.
3. Consult your doctor.
Consult your doctor before taking iron supplements, especially if you are taking other medications or have conditions that affect your medication needs. Be sure to tell your doctor if you have liver or kidney problems, heart disease, asthma, or allergies. If you suspect you have anemia, have a proper blood analysis to make sure it is caused by iron deficiency and not some other condition.
4. Take absorption aids.
To better absorb iron, take nutritional iron supplements along with copper and vitamins A, B complex, and C. Avoid taking antacids and high amounts of vitamin E and zinc, as these can slow down iron absorption.
IMPORTANT: The US Food and Drug Administration (FDA) does not strictly regulate dietary supplements, and many supplements do not contain exactly what their labels say. To stay safe, choose nutritional iron supplements that are GMP-compliant to make sure they do not include harmful additives, such as silica, starch, sugar, and gluten.
It was shown that, even if it seems hard to believe, the initial signs of lupus may appear in the blood, a blood disorder can be the first sign that comes in patients having systemic lupus erythematosus.Systemic lupus erythematosus can show hematological symptoms like anemia, thrombocytopenia, low white blood cell counts and clotting disturbances. That is why, specialists in disorders of the blood can be of real help.
One of the most usual hematological abnormalities that can appear in persons having lupus is anemia. Anemia consists in a reduction in the number of red blood cells and it is recognized by some tests, such as, the hemoglobin concentration in blood, the hematocrit and the red blood cell count.It is known that anemia can have many causes, and in what concerns persons with lupus, anemia can appear because of a chronic inflammation, iron deficiency, prolonged uremia or hemolytic anemia. It is also known that fatigue, which is suffered by many patients having lupus can contribute to the apparition of anemia.
Prolonged uremia, which appears because of an impaired kidney function can lead to anemia. Anemia caused by prolonged uremia can be treated with androgens or erythropoietin, a recently developed hormone having role in the stimulation of red cell production. Sometimes, chronic uremia can determine the apparition of more severe forms of anemia, and that requires blood transfusions.
Prolonged inflammation, which is an important cause of anemia in patients that have lupus, hinders the production of red blood cells by the bone marrow. Because of this inflammation, iron, which is very important in the production of hemoglobin accumulates unused in the marrow tissue. The solution to restore normal red blood cell production is to ease the inflammatory condition.
Iron deficiency is another cause of anemia that can appear because of the blood loss from the body. Drugs that are used in the treatment of lupus can irritate the stomach and produce bleeding and from there results iron-deficient anemia. Iron deficient can become also women that have heavy or frequent menstrual periods.Anemic patients should take some tests for blood loss from the stomach or intestines. It is important to do that, because the source of bleeding must be found and treated.Iron deficient anemia can be corrected in a short time by taking iron tablets.
Hemolytic anemia is a condition that can appear in some people with lupus, usually due to antibodies directed against red blood cells. In this condition, auto-antibodies interact with the red blood cells, and the result is that the red blood cells are removed in the spleen or liver by scavenger cells.Usually, steroids like Prednisone are effective into treating this type of anemia, but there are cases of patients that do not respond to the treatment, and surgical removal of the spleen may be required. Also in severe cases, it is needed a blood transfusion.It is known that a deficiency of thrombocytes, which are tiny particles in the blood, essential for blood clotting causes thrombocytopenia. This leads to bleeding from the gums, nose, or intestines and excessive skin bruising. As some typical signs of thrombocytopenia, we can mention petechiae and pinpoint hemorrhages in the skin.In person with lupus, usually occurs immune thrombocytopenia. This appears because antibodies destroy the platelets, similarly with the destruction of the red blood cells in the autoimmune hemolytic anemia. As a treatment, we can mention steroids like Prednisone and in severe cases splenectomy may be needed.
It was discovered that patients that have lupus produce an antibody called the lupus anti-coagulant. It was seen that some patients with the lupus anti-coagulant tend to form clots abnormally condition called venous thrombosis. That is a paradox that science can’t explain yet.Sometimes, venous thrombosis can associate with pulmonary embolus, and particularly that situation requires treatment with anti-coagulant drugs such as heparin and Coumadin. Lupus anti-coagulant was also detected in cases of recurrent fetal loss, but it is not known if it causes the so-called habitual spontaneous abortion.
Patients with lupus can experience also some abnormalities , like granulocytopenia, which means there is a low granulocyte count, and lymphocytopenia- when there is a low number of lymphocytes. Usually, these abnormalities are harmless and without symptoms, but there can occur severe granulocytopenia, which is usually caused by a reaction to medication. In this case, there must be stopped the intake of the causative drug, and if there is an infection, treatment with antibiotics is required.
Nowadays, there is a great concern about the risk of getting AIDS by blood transfusions. It is good to know that there were developed tests for antibodies against the virus that causes AIDS, and all the blood donors are screened for such antibodies.Of course, the safest thing that can be done is to store your blood for later transfusion, but this is not always practical.It is also possible in some blood banks to designate a member of the family to donate blood for you, but it must be taken in consideration the possibility of blood incompatibility.
pH can be defined as a scale through which you can measures how alkaline or acidic a substance is. This scale has a range of one to fourteen with fourteen being very alkaline, seven being neutral and one being highly acid. The pH level of your blood can be extremely important.
The perfect pH level the human blood is around 7.35 and the human body can go to enormous ends to maintain the level. When the pH levels drops below the required level, it can cause undesirable effects. Red blood cells are the ones which transport oxygen to the cells of your body.
The red blood cells will be moving through the tiny capillaries which can be so small that only one red blood cell can pass through them at a time. They are equipped with a mechanism which keeps them separate from each other. The red blood cells will have a negative charge in them which will make them stay away from each other. By the acids can interfere with this significant mechanism as they are capable of striping the negative charge away from the red blood cells. As a result the red blood cells will clump together and will not flow easily. This can result in the reduction of the oxygen levels which will get into your cells.
Acid can also weaken the red blood cells and can cause their death.
A bad dietary habit of an individual can be the primary reason of an acidic condition of his body. It is pretty fortunate that the acidity in your body can be decreased quickly by adopting some changes. You can do this by just including a bit of alkaline foods in your diet and eliminating some of the acid foods from your diet.
You should get a correct picture of the pH level of your body which will enable you to decide whether you should remove more acid foods from your diet and increase the more alkaline ones. You must test either your saliva or your urine regularly to get the correct PH level situation of your body. You can actually control the acidity of your body by eliminating acid foods you eat and adding the quantity of alkaline foods in your diet.
In addition to this, you can immediately start changing the pH level by drinking the “supergreen drinks”. There are many supplements available such as the Supergreens powder which has a powerful mixture of grasses which are organically-grown, green vegetables and leaves and sprouted grains which will provide the body with a large variety of easily absorbable amino acids, vitamins and minerals. Prime pH will act as an oxygen catalyst in bloodstream. The formulation of this drink will do the alkalizing, oxygenating, neutralizing and thus have a pH balancing effect in the body. It is prescribed to have four liters or one-gallon of water a day. In one liter of water, add one level teaspoon of the ‘SuperGreens’ powder and ten to fifteen drops of the LL Prime PH to get a nutrient-dense, energizing and alkalizing drink.
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Heart disease itself is a serious medical concern. When kidney and heart disease occur in combination, the challenge is even greater.
Kidney and heart disease may begin separately, and then progress together, becoming one disease. Heart disease may also spark the beginning of kidney disease. Whichever occurs first, kidney and heart disease affect each other’s progress.
Since kidney and heart disease are so closely related, anyone who has heart disease, or is at risk for developing it, should ask his or her physician to order urine and blood tests that are designed to identify kidney disease.
Kidney Functions
Most people know that the kidneys remove wastes and fluids from the body. In addition to these functions, kidneys also perform other important jobs. Among them, several are vital to heart health.
* Regulate water in the body
* Regulate blood chemicals: calcium, phosphorus, potassium, and sodium
* Remove drugs and toxins from the body
* Release hormones that regulate blood pressure and create red blood cells.
Kidney Disease Consequences
Kidney disease that is uncontrolled can become chronic kidney disease (CKD). As CKD worsens, the kidneys can not adequately regulate water in the body. The blood may become too thick, placing an increased work load on the heart.
At the same time, blood chemicals will go unregulated. If the heart lacks the important electrolyte chemicals, it cannot function efficiently.
CKD will also allow drugs, toxins, and other wastes in the blood to build to high levels. These high concentrations of toxic materials can take a toll on the whole body, including the heart.
High blood pressure and anemia (low red blood cell count) can be linked to failure of the kidneys to release necessary hormones.
Kidney and heart disease will then become a combined concern.
How to Prevent the Lethal Combo
Early detection of kidney and heart disease is important. Both can be treated more successfully if detected in their early stages.
Ask your physician about these three simple tests: blood pressure, serum creatinine test, and urine test.
If you have high blood pressure, be sure your physician tests for kidney disease. If you have kidney disease, insist that your physician test for high blood pressure. One can cause the other.
The kidney and heart disease combination is most likely to hit those with diabetes, hypertension, and a family history of kidney disease. If you are African American, Hispanic, a Pacific Islander, a Native American, or a senior citizen, you are at greater risk for kidney and heart disease.
Kidney and heart disease do not always go hand-in-hand, but if you have one or the other, you increase the risks of both.
CAUTION: The author is not a medical professional, and offers the information in this article for educational purposes only. Please discuss it with your health care provider before relying on it in any way.
Anemia is a condition that occurs in pets when their red blood cell count is lower than normal. Red blood cells are responsible for carrying oxygen to different parts of the body. The hemoglobin in the red blood cells causes blood to have a red tint and is the responsible party for delivering the oxygen. If the number of red blood cells being produced drops then your pets body has to work much harder to get oxygen to different parts of the body. Anemia causes animals hearts to beat faster, causes a depressed mood, makes their gums turn pale and fatigues them.
Anemia can be extremely serious if it is not caught and treated right away. A young dog or cat are at an added risk for developing anemia if they are infested with fleas or internal parasites. Their bodies are much more easily weakened when their blood is being fed on. Be sure to get rid of fleas and worms right away if your dog or cat is very young.
Anemia can be caused by three categories of problems – loss of blood, low red blood cell production and hemolysis.
Many things can cause the loss of blood. The most common are injury or trauma to internal organs, parasites and blood vessel damage. There are also a whole group of substances that can cause damage leading to blood loss. Make sure your pet stays away from cooked onions, any type of OTC or prescription drugs, propylene glycol, zinc and copper.
Hemolytic anemia is the most common form of anemia found in pets. It is caused by immune-mediated diseases. When this occurs the body actually attacks its own red blood cells rather than the germs that it would normally attack. Certain breeds of dogs are more prone to get this – including poodles, spaniel breeds and Old English sheepdogs.
If anemia is serious your pet might need medication and an IV of blood or fluids. Just make sure that you get them to the vet right away if you are seeing any symptoms.
Make sure that you keep an insect and worm repellant on your pet, feed them a balanced diet and give them regular exercise. Dandelion, ashwagandha and milk thistle can all be used to boost the immune system and levels of hemoglobin. Make sure that you take extra care when your cat or dog is really young. They are more likely to get anemia when they are puppies and kittens.









