Leukemia severely affects a person’s immune system; the disease is characterized by low levels of leukocytes of white blood cells, which play an important role in the body’s defenses against disease. This disease can lead to other complications such as infections. However, for people who already have compromised immune systems, such as children and the elderly, developing leukemia can have some severe effects and complications. For children, the effects of leukemia can be very pronounced because battling the disease can take a toll on their fragile bodies.
Types of childhood leukemia
Just like in adult leukemia, children who develop the disease suffer either from large numbers of abnormal white blood cells or low levels of the white blood cells. Among cancers in children, leukemia accounts for about 25% of cancer cases. There are also different types of leukemia among children, categorized into two major categories: acute and chronic. Acute leukemia, or rapidly developing leukemia, is further divided into two types: Acute Lymphocytic Leukemia (ALL) and Acute Myelogenous Leukemia (AML). Acute leukemia accounts for 98% of all cases of childhood leukemia, with ALL being the most common. Chronic leukemia, or slowly developing leukemia, has only one type, which is Chronic Myelogenous Leukemia (CML), and it is very rare.
Symptoms and Treatment
The symptoms that a child with leukemia exhibits are similar to the symptoms that adults with the disease exhibit. Mostly, the symptoms are manifestations that the child’s immune system is compromised, including increased episodes of fever and other infections. Children with leukemia also suffer from anemia and the other blood abnormalities found in most leukemia cases. In addition, other symptoms include bruising and bleeding very easily, pain in the bones and the joints, swollen lymph nodes, malaise, and a poor appetite.
Usually, ALL is treated with chemotherapy. However, the dosage differs from what is given to adults. The medication that is given during this therapy is very potent, which is why for children, smaller dosages are given.
The effects of leukemia can be very hard to deal with, especially for children whose immune systems can be severely compromised by the disease. However, statistics show that children with this disease exhibit some of the highest remission rates, which means that with proper treatment, the chance of beating this disease is very high among children.
Posts Tagged ‘Effects Of Leukemia’
The treatment of leukemia involves various cancer therapies and long-term courses of specific medications. There are many forms of treatment for leukemia and most of them have pronounced side-effects. Although the medical treatments available today are effective in achieving complete remission, they also trigger serious undesirable effects among patients with leukemia. Considering this fact, medical scientists nowadays focus on improving the efficiency of cancer medications with minimal side-effects.
The improved version of the leukemia drug ATRA (all-trans retinoic acid) is considered to be a safer and a more reliable alternative to prolonged chemotherapy and traditional cancer medications. The enhanced version of the drug ATRA is Lipo-ATRA, a more advanced and effective cancer medication. Unlike the old version of the drug, the active agent of Lipo-ATRA is covered with a layer a fat. Its inventors claim that Lipo-ATRA remains inside the human body for longer periods of time, thus having increased efficiency in fighting leukemia cells. In addition, Lipo-ATRA can be administered intravenously, allowing the drug to act a lot quicker in fighting the disease. Thanks to its long-term action, Lipo-ATRA can also minimize the risks of relapse.
During the trial period, Lipo-ATRA has proved to be very effective in overcoming acute myelogenous leukemia (AML). Patients with AML that have been administered the enhanced version of ATRA have experienced a complete remission and they have remained asymptomatic for long periods of time. The majority of patients with AML have even exceeded the critical five-year period of remission, thus being completely cured.
Medical scientists are very satisfied with the potential and the safety of the new drug. They sustain that Lipo-ATRA is a reliable replacement for traditional chemotherapy. Medical scientists explain that more than a third of patients with acute myelogenous leukemia who receive Lipo-ATRA can be spared of prolonged chemotherapy. Considering the fact that the new drug acts very well on its own, patients often don’t require other adjutant cancer therapies or treatments.
In the trial period, the new drug Lipo-ATRA was tested on 34 patients with acute myelogenous leukemia (AML). In the initial stages of treatment, Lipo-ATRA was administered along with idarubicin, a strong cancer medication. When patients began to achieve remission, Lipo-ATRA was administered without idarubicin. The effects of Lipo-ATRA were remarkable, as 10 patients among the 34 that participated to the study remained in remission for more than 5 years even after they stopped receiving adjutant chemotherapy drugs.
Thanks to its efficiency in curing leukemia and thanks to its fewer side-effects, Lipo-ATRA is considered to be the best option in overcoming the disease in present. An appropriate substitute for traditional chemotherapy, Lipo-ATRA may soon revolutionize the treatment of leukemia.

