You need to be vigilant about low as well as high white blood cell count. A low count may be brought on by treatments for cancer. If you have cancer, your oncologist and your hematologist will monitor your white cell counts very closely. Low white cell counts can bring along with them the risk of complications.
What is your physician looking for when he does blood work? When he checks your complete blood count, he is looking for:
Platelets – these help your blood to clot. A low count in platelets may mean your body’s blood won’t be able to clot itself.
Red Blood Cells – these carry oxygen through all the parts of your body. Their ability to do this depends on your body’s level of hemoglobin. If your hemoglobin count is low, it makes your system work harder to take oxygen to all the parts of your body, and results in anemia. You may feel short of breath and overly tired, if you are anemic.
White Blood Cells – these help your body to cast off infection and disease. A low white count means your body is more susceptible to disease. A high white blood cell count means that your body is probably already fighting an infection somewhere. Your doctor will determine where the infection is, so it can be treated.
At times, your physician may want to run what’s called a CBC on your blood. This is called a complete blood count, and is useful in telling your physician what is happening in your body.
In addition to a high white blood cell count, your health care provider will also check your blood for low white blood cell counts. Sometimes this is caused by some chemotherapy drugs, which can cause damage to your bone marrow. Bone marrow is responsible for making blood cells, and chemotherapy kills cells within your bone marrow. Your physician will be able to tell you if the treatment plan that he is putting you on could result in a low white blood count.
If your white count is high, that will tell your health care provider that your body is most likely fighting an infection somewhere, and he will then isolate it and treat it with medications, where possible, so that your body does not need to produce the excess of white blood cells.
If you have a low red count in addition to a high white count, you may be suffering from anemia. If you are often short of breath and fatigued, anemia may be the cause. Ask your physician to test for anemia if you are experiencing these symptoms. In some cases, your fatigue will be so severe that you may need to adjust treatments you receive for cancer or other diseases, in order to allow your body to produce more red cells. The white cell count may increase if infection is present.
Posts Tagged ‘Chemotherapy Drugs’
Considered to be a benign disease for years, Myelodysplastic Syndrome (MDS) is nowadays known to pose a serious threat to people it affects. Recent studies have revealed that MDS is actually a malignant disease that can further lead to leukemia. Due to this fact, Myelodysplastic Syndrome is also referred to as pre-leukemia disease.
Similar to leukemia, MDS triggers an overproduction of abnormal blood cells that eventually outnumber their healthy counterparts. The cells involved in causing the disease are called blasts and they originate in the bone marrow. Dysfunctional blasts multiply at abnormally fast rates and accumulate in the marrow or in the bloodstream. These functionless cells perturb the production of normal blood cells, causing a decrease in the number of red blood cells, white blood cells and platelets. As a result, people who suffer from MDS also have anemia, (due to fewer red blood cells), impaired immune system (due to fewer white blood cells) and experience slow healing (due to fewer platelets).
Many patients diagnosed with MDS are at risk of developing leukemia. In order to block the progression of MDS and to prevent the occurrence of leukemia, most patients receive treatments with decitabine, a new drug that is currently under testing.
Although most patients diagnosed with MDS respond well to treatments with mild chemotherapy drugs and decitabine, they commonly experience relapse after completing the prescribed course of medications. MDS has a pronounced recurrent character and despite its high curability in the initial stages of the disease, it becomes very difficult to treat in later stages of evolution.
Oncologists have noticed the fact that patients who relapse also become less responsive to second treatments. The exact reasons why most patients with MDS fail to respond to re-treatment are still unknown. However, this problem may be corrected by extending the duration of initial treatments. Medical scientists explain that a single long-term course of chemotherapy drugs and decitabine may provide better results than frequently repeated shorter treatments. They sustain that by extending the treatment with mild chemotherapy drugs and decitabine beyond the margin of remission, patients with MDS are less likely to relapse. In addition, medical scientists claim that patients who achieve remission should follow ongoing maintenance treatments in order to prevent the recurrence of the disease.
Recently conducted experiments have confirmed the fact that long-term treatments provide better results than repeated treatments in overcoming MDS. Patients who receive short-term treatments not only experience relapse, but they are also more exposed to developing acute leukemia and other severe forms of blood cancer. In order to prevent this from happening, an extended low-dose initial treatment with decitabine followed by maintenance treatments may be the best option for patients diagnosed with MDS.
This is the chemo treatment you can take at home. So what exactly is oral chemotherapy? The term refers to the way of administering chemotherapy by taking chemo drugs by mouth. Chemotherapy is medicine used in treating cancer and the ways to apply it are multiple. Nowadays, due to progress in cancer treatments and research, patients benefit from many different types of chemotherapy that can be taken in as tablet, liquid or capsule. And any drug that can be taken by the mouth to treat cancer belongs to oral chemotherapy. You no longer have to worry about your doctor trying to find that vein in your arm. You have the option of taking your medicine orally by capsule or pill. Although taken chemo orally is a whole lot easier, the effects of pills will be the same, with the mention that they are more likely to trigger adverse reactions because of the impact on the digestive tract.
You will always have some chemotherapy drugs that can never be taken orally as they cannot be absorbed in the stomach or they can cause harm if swallowed. As a matter of fact, most of the chemotherapy drugs are introduced into the patient’s veins by means of injecting it through an intravenous line. In the case of oral chemotherapy, the treatment is more facile as the patient can do it at home, without being forced to go to hospital every time it is applied.
How does one administer oral chemotherapy? It is best the patient take this medicine in cycles. By taking oral chemo in cycles this will help to greatly reduce the possibility in damaging healthy cells. Obviously, the doctor is the one who will decide how frequently (daily, weekly, monthly, etc) medication will be taken. Another, the doctor’s job is to discussed with the patient what lies ahead in terms of challenges, difficulties and success rate. Only when one is informed and convinced of the efficiency of the treatment, can one decide to begin it.
Although oral chemotherapy drugs are not as strong as the others and although they do not affect the patients’ stomach, there are side effects. Tiredness for a few days after beginning the treatment, nausea and vomiting, possible change in the amount of blood cells (anemia), lower capability of the blood to clot, diarrhea or constipation, flu-like symptoms, hair loss, increased risk of infection, kidney or bladder problems, mouth, gum and throat sores, pains, and nerve and muscle problems, are some of the long list of side effects when it comes to oral chemotherapy. The same side effects as those chemo drugs taken intravenously. As with any of these side effects it is advisable that patients address their doctors for advice and help. Although you will be taken your chemo treatments at home, you will still have to regularly visit your doctor without the hospital stays.

