Posts Tagged ‘Central Nervous System’



Cocaine is a very powerful stimulant that has significant affects on the brain and has an extremely high potential for drug addiction.

A highly addictive substance, Cocaine is a powerful stimulant derived from the leaves of the Coca plant native to South America. It is usually seen in a powdered form, as a powdered hydrochloride salt which is most commonly snorted, although it is also dissolved and injected.

Crack is another form of cocaine – this is a crystalline form of cocaine which has not been treated with acids to produce the familiar powdered form. Crack cocaine is heated and the vapors produced inhaled to produce an intense high, much as with the practice of “freebasing” which preceded the large scale production of Crack cocaine.

Cocaine is a stimulant. Like other stimulants, cocaine works on the central nervous system to stimulate the production of dopamine in the brain. It is dopamine which produces the “high” of the drug. This chemical is produced naturally by the brain in response to certain stimuli; but cocaine works by preventing the reuptake of dopamine, which intensifies the pleasure signals the chemical produces.

This disrupts normal brain function and produces a feeling of euphoria. However, habitual use of cocaine essentially rewires the brain, causing physical addiction. It actually can change the physical structure of the brain. In addition to producing addictive patterns of behavior, regular users of cocaine experience an increased tolerance to the drug so that larger and larger amounts are needed to produce the same sort of euphoric state. Along with this comes a much higher risk of severe physical and psychological effects.

How Does Cocaine Negatively Impact Health?

Cocaine abuse has a number of different negative effects on physical health. Cocaine causes the pupils to dilate, blood vessels to constrict and an increase in heart rate, blood pressure and body temperature. The drug can also cause digestive problems including nausea and abdominal pain, as well as headaches. Cocaine addicts may also have a tendency towards becoming malnourished, since the drug is a powerful appetite suppressant.


The negative health impacts of cocaine may vary with the method of ingestion. Snorting cocaine can cause nosebleeds, hoarseness, a runny nose and a loss of one’s sense of smell. Injecting cocaine exposes users to the risk of contracting HIV and other diseases if they share needles; allergic reactions are also not uncommon in cocaine-injecting users. Cocaine users can also run the risk of gangrene in the bowels due to reduced circulation. Heavy regular use of cocaine can cause anxiety, irritability and paranoid though patterns. Some cocaine users even experience psychotic episodes, sometimes developing into an actual paranoid psychosis.

Cocaine users are always at a higher risk of strokes and heart attacks, no matter how often they use cocaine or through what method the drug is ingested. There are those who have suddenly died from a cardiac arrest the very first time they have used the drug. Most cocaine related deaths are due to a sudden cardiac arrest upon taking the drug.



While many research studies conducted have shown that many individuals suffering from major depression abuse alcohol to self-medicate thereby causing their symptoms of depression to worsen, newer epidemiological studies have shown that alcohol abuse may in fact be one of the risk factors in the development of this illness.

However, scientists and researchers still believe that the majority of individuals who suffer from major depression develop this illness due to a combination of factors that can include, biological, environmental, and personality or lifestyle.

A twenty five year study conducted in New Zealand on individuals seventeen to twenty five years of age concluded that at any of these ages those who were dependent upon or abused alcohol were one point nine times more likely to suffer from major depression.

Alcohols Physiological Effects that may play a Role in Depression

Medical experts say that alcohol lowers the levels of the brain neurotransmitters or chemicals serotonin and norepinephrine which scientists believe are responsible for controlling mood. Alcohol depresses the central nervous system and the brain; therefore, when alcohol is consumed it can cause or worsen the symptoms of depression.

Alcohol abuse also causes many health problems overall as well as work, family, and relationship problems. These factors compounded with the fact that the alcohol itself is a depressant, significantly increases the risk for depression. Scientist and researchers have also found certain genes that are associated with depression and other mental illnesses can be activated or triggered by stress or the abuse of drugs and alcohol.

When Alcohol and Depression Coexist

Estimate show that as many as forty percent of individuals who consume heavy volumes of alcohol either have or exhibit the symptoms of depression. These estimates also state that when these same individuals are not consuming large volumes of alcohol only five percent of men and ten percent of women will exhibit the symptoms of clinical depression and these figures closely resemble the rate of depression among the general population. It is also estimated that between five and ten percent of individuals who have a depressive disorder also have a problem with alcohol and/or drugs.

Unfortunately, it is extremely common for depression and alcohol abuse to coexist and this creates an extremely dangerous combination. Alcohol causes individuals to lose their inhibitions as well as impair their judgment and can lead to impulses as well as aggression and violent behavior.

These factors combined with depression create an extremely high risk factor for suicide as estimates show that the rate of suicides as well as attempted suicide is much higher among individuals who abuse alcohol.

Typically when an alcohol problem and depression coexist, the alcohol problem will be treated first in an attempt to relieve the symptoms of depression. If the symptoms of depression do not improve after an individual has been treated successfully for their alcohol problem, they will then be treated specifically for their depression.



Prescription drug addiction is becoming a major problem in America. Prescription drugs are being prescribed for a wider variety of reasons and quite frequently, greatly increasing the chances that they will be misused. There are several disturbing prescription drug addiction statistics that are worth mentioning.

One sad prescription drug addiction statistic reported by the U.S. Department of Health and human services is that people 60 years old and up are the age group most likely to be addicted to prescription drugs. Furthermore, as of 2000, over 17% of people over age 60 abuse prescription drugs, many of them doing so unwittingly.

Another disturbing prescription drug statistic is that prescription drug abuse is rising fastest among people 12 to 25. Since the mid 1980′s, prescription drug abuse has increased fivefold. One reason for this is that many young people believe that prescription drugs are safe alternatives to illegal drugs. Many of these people don’t know that prescription drugs are addictive and can lead to serious health problems if misused. It is reported that females are more likely to abuse and become addicted to prescription drugs than males are in this age group.

While most people who are addicted to prescription drugs abuse opioids like OxyContin and Vicodin, the number of young people who abused CNS (central nervous system) depressants rose by 50% in just one year, between 1999 and 2000.

The illegal sale of prescription drugs has increased enormously in recent years. The vast increase in the availability of prescription drugs increases the numbers of addicts, because more people have access to the drugs. Modern computer technology makes it very difficult for the authorities to track down operators of websites that sell prescription drugs over the Internet without requiring a prescription.

These prescription drug addiction statistics are disheartening, but the more people are aware of the problems caused by prescription drug addiction, the more likely they are to avoid misusing them or seek help if they already have a problem.

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The brain is the organ in a person’s skull that controls the functions of all of the other organs. Together, the brain and spine make up the central nervous system. The brain is responsible for the experience of the five senses (taste, touch, sight, hearing and smell). The brain is also the seat of thought, language, personality, creativity and memory. The brain controls movement, sensation, balance, and coordination. In order to do its job, the brain requires an enormous amount of the oxygen and nutrient energy that a person takes in regularly.

The brain is comprised of nerve cells (called neurons) which carry signals, and the cells which support the nerve cells (called glial cells ). There are a number of different types of glial cells, all with different names and functions. The glial cells outnumber the neurons in the brain by a ratio of 10:1

Brain Tumor Symptoms

Depending on the location and size of the tumor, symptoms experienced by each patient may vary. Most of the common symptoms are due to increased intracranial pressure as the growing tumor affects surrounding structures:

* Frequent headaches (reported by 50% of patients)

* Blurry vision

* Nausea and/or vomiting

* Personality or cognitive changes

Other symptoms are site-specific, including seizures, speech impairment, weakness or numbness on one side and problems with coordination, balance or mobility.

Types of Brain Tumors

There are many different types of brain tumors, based on what cells are affected and how they appear under a microscope. Tumors can be classified into four general categories:

1)Gliomas

2)Astrocytoma

3)Grade I (pilocytic astrocytoma): slow growing, with little tendency to infiltrate surrounding brain tissue. Most common in children and adolescents.

4)Grade II (diffuse astrocytoma): fairly slow-growing, with some tendency to infiltrate surrounding brain tissue. Mostly seen in young adults.

5)Grade III (anaplastic/malignant astrocytoma): these tumors grow rather quickly and infiltrate surrounding brain tissue.

6)Grade IV (glioblastoma multiforme, GBM): an extremely aggressive and lethal form of brain cancer. Unfortunately, it is the most common form of brain tumor in adults, accounting for 67% of all astrocytomas.

7)Oligodendroglioma

8)Ependymoma

Tests on your cancer cells

Your breast cancer cells can be tested to see if they have ‘hormone receptors’ or biological therapy receptors. There are oestrogen receptors and progesterone receptors. You may hear your doctor talk about ‘your oestrogen receptor status’, ‘ER status’ or ‘PR status’. Sometimes, doctors may say you are ‘ER positive’ or ‘ER negative’.

Treatment

1)Surgery

When possible, brain tumors are removed through surgery. While many can be removed with little or no damage to the brain, others are located where surgical removal is difficult or impossible without destroying critical parts of the brain.

Brain damage caused by surgery can lead to partial paralysis, changes in sensation (feeling), weakness and poor thinking. Even so, removing a tumor is necessary when it threatens important brain structures. Even when it can’t cure a malignancy, surgery can help reduce the size of the tumor, ease symptoms and help determine the type of tumor

2)Radiation Therapy

3)Chemotherapy



A drug is a chemical substance which is prescribed by the Doctor to treat the illness and also the level of dosage is decided by the Doctor. But some drugs are used illegally, which affects the central nervous system and make the person to become addicted to that particular drug on usage. The drugs which come under this category are heroin, cocaine etc. The level of dosage is highly important, because heavy doses are harmful.

Many youngsters become addicted to drugs, due to bad companion. Once the person becomes dependent on drugs, it takes some time to recover them completely. So to treat and to bring them back to their normal life, there exists a special care and treatment centers called drug rehabilitation center. This type of center conducts necessary programs and treatments to help these people to overcome their drug addiction. It is necessary to consult a experienced healthcare professional in Okanagan regarding drug rehabilitation (recovery from drugs).

Programs carried out in Okanagan drug rehabilitation centers

Short-term, long-term, inpatient, outpatient and residential are some of the programs offered in the Okanagan centers. The programs for the patients are selected depending upon their stage and severity. Each and every program helps in recovery as well as educates (counsels) them to a certain extent. Let us view these programs in detail.

Short-term programs – The duration of this program is very short (from 3 to 6 weeks). The patient’s physical, mental and behavioral factors are taken into consideration. Here the patients are asked to follow a twelve step plan which helps them to restore their health completely.

Long-term programs – This program takes some months to 1 year to cure the patient. Here the patients realize the psychological effects caused as a result of addiction. As this program takes some long duration, the patients are able to remobilize themselves and reduce the return of the disease.

Outpatient treatment – Here the patient involves in activities such as counseling, which helps them to identify and recognize their goals especially their behaviors. It is designed in such a way, based on the needs and conveniences of the patient.

Inpatient treatment – The facilities in inpatient department provides certain wellness programs, counseling and detoxification, a variety of lessons on drug abuse and programs to kick out the drug addiction habit from you.

On the whole, it is your option to choose the program that suits you.

How to choose a drug rehabilitation center in Okanagan and Kelowna?
1. The family and friends shall select the right rehab center for the patient. Many issues are to be considered while selecting a rehab center such as the type of the programs offered and their cost factors.

2. Most of the rehab centers are non profit organizations, so you have to gather all their information in detail, before choosing a particular center.

3. Collect information on the costs of treatments and the programs offered in various centers and then choose the one, which suits you.



When it comes to addictive drugs that are often abused, cocaine leads the way as one of the most powerful illegal substances on the street. Many who have dabbled in the use of cocaine (even if only for one time), the chances of becoming hooked are quite high. One can never truly control their body’s need for the drug once it has undergone an experience. Numerous individuals will continue to use cocaine, eventually developing an addiction that wreaks havoc on their social and personal lives, as well as job performance, emotions, and health.

Cocaine is often sniffed, snorted, injected, or smoked (which involves the use of crack cocaine or free-base). Snorting cocaine powder through the nose allows the drug to enter the bloodstream through the nasal tissues. The use of a needle releases the drug straight into the bloodstream, while smoking sends cocaine vapors into the bloodstream through the lungs. Injecting and smoking quickly intensifies the effects of cocaine because it makes contact with the bloodstream faster than other methods of use.

Effects of Cocaine Abuse

Cocaine users often suffer from the effects of the drug throughout their central nervous system. Peripheral blood vessels become constricted, pupils dilate, and an increase in blood pressure, heart rate, and temperature may arise. Some users may succumb to periods of anxiety, irritability, and restlessness. In the worst cases, cocaine users may experience sudden death at first use, but at any time, the threat of unexpected death may occur. High doses of cocaine or constant use may also lead to paranoia, aggressive tendencies, nasal damage (when snorting), seizures, or cardiac arrest.

Getting Help for Cocaine Addiction

Since cocaine use is a dire problem in today’s society, there are many different resources that help people overcome their addiction. A wide range of treatment programs and opportunities are available for cocaine addicts, including both inpatient and outpatient techniques. Self-help groups are a popular way that cocaine addicts cope with leaving their drug of choice behind.

Many of these associations work from a 10- or 12-step model that aims to prevent a relapse, as well as help individuals stay on track. Medication, counseling, and additional meetings also help break the cycle of drug addiction. To find a self-help group, a wealth of outlets can guide one in the right direction, such as doctors, counselors, the phone book, library, and across the Internet.



Diabetic ketoacidosis is a life threatening condition that all diabetics are susceptible to and is brought on by a deficiency of insulin. Type 1 diabetics are more likely to suffer from this condition, but all diabetics should be aware of its symptoms and life-threatening affects. The mortality rate is about two percent of the people who get it.

Ketoacidosis occurs when glucose cannot be used as an energy source by the cells of the body, or when endogenous sources of energy are not available. When this happens the body will begin to break down fats and proteins for it energy source, in effect cannibalizing itself to survive. This leads to ketosis, which is an abnormal accumulation of ketones caused by metabolism of fatty acids for energy with little carbohydrate metabolism taking place. This can cause a rapid decrease in blood pH resulting in ketoacidosis and a dumping of ketone bodies into the urine.

This condition results in hyperglycemia that causes osmotic diuresis, leads to dehydration, and precipitates lactic acidosis. Lowered pH, resulting from the acidosis, stimulates the respiratory center and produces deep, rapid respirations known as Kussmaul’s respirations. Large amounts of ketone bodies in the body also produce a fruity or acetone odor on the breath. For many people unfamiliar with this condition it may actually smell as if the person has been drinking alcohol.

If the ketoacidosis in the diabetic is not recognized and treated quickly, the acidosis and dehydration can disrupt heart activity and oxygen transport. It will also severely depress the central nervous system which leads to loss of consciousness and possibly coma and death. Other symptoms that may occur before a loss of consciousness include lethargy, nausea, muscle aches, rapid breathing (Kussmaul’s respirations), low blood pressure, rapid heart rate, difficulty catching ones breath, and dehydration. Other life threatening conditions brought about by this condition include kidney failure and heart attacks.

Aside from an insulin deficiency there are several other common conditions that can lead to diabetic ketoacidosis. These include over eating, infection and other stresses such as trauma, surgery, emotional stress and heart attack.

It is important for anyone with diabetes to be aware of the warning signs of diabetic ketoacidosis. Consulting with one primary care physician is the first step to understanding this condition and taking the proper steps to avoid it affects. By following a sound diabetic diet plan and treatment regiment the chances of suffering from ketoacidosis are greatly diminished. But even then anyone with diabetes should remain ever vigilant against this potentially fatal condition.

Incoming search terms for the article:

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AML, (acute myelogenous leukemia), is an aggressive cancer of the bone marrow and blood. It is the most common type of leukemia. AML is also known by the following names-acute myeloblastic leukemia, acute myeloid leukemia, acute granulocytic leukemia or acute nonlymphocytic leukemia. Blood cells are malformed and useless. The cells can accumulate in parts of the body.

Acute myelogenous leukemia statistics

o Rare in people under 40 years old

o More common in men than in women

o Average age is 65 years old

o 5-year survival rate

o under 65 years old-33%

o over 65 years old-4%

o 2007 it is predicted there will be 13,000 cases (majority will be adults)

The symptoms of acute myelogenous leukemia include abnormal blood counts, a general run-down, unwell feeling that never gets better, reoccurring infections, swollen lymph nodes, and bone/ joint pain. Symptoms are acute (comes on suddenly, and accelerates quickly) instead of chronic (mild symptoms that gradually worsen over years).

When the malformed cells collect around parts of the body, it can cause skin, lung, central nervous system, kidney, and even testicle problems. Initially, acute myelogenous leukemia may mimic other conditions. Blood tests identify the possibility of AML. The final diagnosis is usually made after a bone marrow test and sometimes by a spinal tap, also known as a lumbar (lower spine) puncture (LP).

There are several types treatments available, one or more will be used to treat a dignosis of AML.

Chemotherapy-strong drugs taken orally or intravenously that kills the cancer cells. Occasionally it’s injected directly into the spine. It is a systemic treatment because it travels throughout the whole body.

Radiation-high energy rays like X-rays kill the cancer cells

Bone marrow transplants-unhealthy cancer producing bone marrow is destroyed and replaced with matching bone marrow.

Immunotherapy-stimulates the immune system to destroy cancer cells or boosts natural defenses. It can be a made naturally or artificially.

Risk factors for AML

o Previous chemotherapy or radiation treatments

o Exposure to radiation and chemicals like benzene

o Genetic disorders like Downs Syndrome

o Smoking

o Blood disorders like myelodysplasia

People with risk factors should watch more closely for symptoms of AML because early treatment increases survival rate.



Ginseng is an herb that is extensively used in oriental medicine to treat all kinds of diseases. Korean Ginseng, also known as Panax or Chinese Ginseng, is considered the most efficacious among the different types of ginseng available. It contains a group of compounds called ginsenoids which are said to be responsible for the preventative and curative effects of ginseng.

Because of the potency of the herbs in combating many different conditions like diabetes, cancer, fatigue and stress, and others, several studies are performed the world over to understand the secret behind the efficacy of this herb. A group of researchers studied the effects of ginseng, especially its potential to cure cancer, and published their findings in the Chinese Medicine Journal. They opined that ginsenoids act as functional ligands to activate different steroid hormone receptors. Through such mechanisms, ginseng acts on the body in a similar way as steroid hormones.

Ginseng has demonstrated therapeutic effects on the cardio vascular system, central nervous system, immunity, metabolism, endocrine functions, stress and aging. Ginseng has also been extensively used in oriental medicine to treat cancer.

Studies reveal that the pharmacological effects of ginseng are due to its bioactive constituents like ginsenoids, saponins, peptides, polysaccharides, polyacetylenes, fatty acids, minerals and vitamins. According to a report published in the Chinese Medicine Journal, ginsenoids have anti-tumor effects and has the ability to induce apoptosis or death of the tumor cells, anti-proliferation, anti-invasion and metastasis, as well as anti-angiogenesis.

Metastasis is the process by which cancer spreads from the place where it first formed as a primary tumor to other parts of the body. Metastasis is caused due to the cancer cells acquiring two distinct abilities – increased motility and invasiveness. It involves a complex process of angiogenesis (the process of developing new blood vessels) and cell interactions. By inhibiting tumor induced angiogenesis, ginsenoids control metastasis. Ginsenoids are also useful in inhibiting invasiveness of cancer. They have been shown to inhibit lung metastasis, and reduce the bulk of tumors in melanoma, breast, gastric and lung cancers. The only way to cure cancer is to control metastasis and destroy the tumor cells.

Ginseng contains several compounds that have been found useful in inducing cell death in ovarian cancer cells, prostrate cancer cells and lung adenocarcinoma cells. The researchers say that the way in which ginsenoids help in elimination of tumor cells may be by inducing cell death.

Ginsenoids also demonstrate preventative effects. They inhibit the cell cycle progression and have been known to stop the cell growth in tumor cell lines of lung tumor, prostrate cancer, leukemia and liver cancer.

Researchers say that ginsenoids called Rg3 and Rh2 have emerged in China ad Taiwan as anti cancer drugs. Rg3 suppresses tumor angiogenesis, prevents adhesion, invasion and metastasis of tumor cells. It was also found that chemotherapy supplemented with Rh2 was 60% more effective than chemotherapy alone. Rh2 also showed promise to mitigate adverse effects of chemo like hair loss, nausea, anemia and poor appetite.

Both Rg3 and Rh2 are extracted from Korean red ginseng. This magical herb continues to astound scientists all over the world and provide people with daily miracles.